Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:54 AM
Ignite Modification Date:
2025-12-25 @ 2:54 AM
NCT ID:
NCT06704633
Eligibility Criteria:
Inclusion criteria
* Symptomatic heart failure NYHA class II-IV and
* Left ventricular ejection fraction (LVEF) ≤40% and
* Treatment with an ACE Inhibitor or an ARB, beta-blocker, and spironolactone in recommended dosages for at least 3 months, and
* Adherence to this therapy of at least 80%.
Exclusion criteria
* Pregnancy
* Systolic blood pressure of less than 95 mmHg,
* eGFR below 30 ml per minute per 1.73 m2 of body-surface area
* Serum potassium level of more than 5.4 mmol per liter
* History of angioedema
* Unacceptable side effects prior during receipt of ACE inhibitors or ARBs
* Inability to sign an informed consent form.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06704633
Study Brief:
Protocol Section:
NCT06704633