Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:53 AM
Ignite Modification Date:
2025-12-25 @ 2:53 AM
NCT ID:
NCT04190433
Eligibility Criteria:
Inclusion Criteria:
* \>= 18 years of age.
* New diagnosis of reduced cardiac function.
* Any prior anthracycline-based cancer therapy for hematological malignancy, breast cancer, or sarcoma.
Exclusion Criteria:
* History of heart failure (HF) of any class and type, or diagnosis of cardiomyopathy prior to anthracycline therapy.
* On active therapy with a fibrate, niacin or eplerenone, or statin.
* History of myopathy/rhabdomyolysis.
* History of statin intolerance.
* Active treatment for hyperlipidemia.
* History of gout.
* Active treatment for liver disease.
* Unexplained persistent elevations of serum transaminases (above upper limit of normal over two weeks).
* Pregnancy.
* Breast-feeding.
* Hyperkalemia (above upper limit of normal).
* Addison disease.
* Estimated glomerular filtration rate (eGFR) \< 30 mL/minute/1.73 m\^2.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04190433
Study Brief:
Protocol Section:
NCT04190433