Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:53 AM
Ignite Modification Date:
2025-12-25 @ 2:53 AM
NCT ID:
NCT03688633
Eligibility Criteria:
Inclusion Criteria:
* Patients aged 18 years and over and to be treated with Vincristine for non-Hodgkin B lymphoma (first line treatment)
* All the patients have to be treated with the same chemotherapy protocol (CHOP with or without Rituximab) to avoid confounding factors
* Normal renal function as measured by CKD-EPI \> 30 mmol / min / 1.73 m2
* Serum potassium \< 5.5 mmol / l
* Systolic arterial pressure \> 100 mm Hg (lying and standing position)
* affiliated with a social security
* For women of childbearing age: under "highly effective" contraception and negative pregnancy test at inclusion. Highly effective contraception:
* Combined hormonal contraceptive (containing estrogen and progesterone) (oral, intravaginal, or transdermal) or only progesterone (oral, injectable or implantable),
Exclusion Criteria:
* Patients with pre-existing neuropathy, Chronic ethylism, HIV infection, etc.
* Patients under guardianship or unable for another reason to give informed consent.
* Intolerance to sartans
* Intolerance to excipients : galactose , lactose.
* Patients already treated with ACE inhibitors, ARBs or/and diuretics sparing
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT03688633
Study Brief:
Protocol Section:
NCT03688633