Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:45 AM
Ignite Modification Date:
2025-12-25 @ 2:45 AM
NCT ID:
NCT02670733
Eligibility Criteria:
Inclusion Criteria:
1. Age 18 years and above;
2. Glasgow Coma Score ≤ 8;
3. Ventricular ICP monitor was placed for ICP monitoring and cerebrospinal fluid (CSF) drainage;
4. Need for mechanical ventilation with PEEP;
5. ARDS was diagnosed according to Berlin Definition.
Exclusion Criteria:
1. Hemodynamic instability requiring more than 10 μg/kg/min dopamine or more than 0.5 μg/kg/min norepinephrine;
2. ICP \> 25 mmHg;
3. Esophageal varices;
4. History of esophageal or gastric surgery;
5. Evidence of active air leak from the lung, including bronchopleural fistula, pneumothorax, pneumomediastinum, or existing chest tube;
6. History of chronic obstructive pulmonary disease.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02670733
Study Brief:
Protocol Section:
NCT02670733