Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:43 AM
Ignite Modification Date:
2025-12-25 @ 2:43 AM
NCT ID:
NCT04121533
Eligibility Criteria:
Inclusion Criteria:
* Unilateral knee pain, weakness, and impaired physical activity
* Older than 18 years of age but younger than 60 years of age
* Reportedly physically active (minimum of 30 minutes of continuous exercise or physical exertion 3 times per week during the previous year)
Exclusion Criteria:
* Bilateral symptoms of hip, knee or ankle osteoarthritis
* Recent (within 2 years) surgery on the symptomatic or non-symptomatic limb
* History of metabolic bone disease
* History of any skeletal muscle pathologies
* History of cardiac or peripheral cardiovascular system abnormalities
* History of clotting disorders
* History of coronary artery disease, peripheral vascular disease, or stroke
* History of cancer
* Use of warfarin or other anti-coagulants prior to study enrollment
* Use of cholesterol lowering medication
* History of high cholesterol or triglycerides
* History of high blood pressure
* Diagnosed with diabetes mellitus
* Impaired liver function
* Impaired kidney function
* Pregnant
* Daily dietary supplement or vitamin use during the previous year
* Use of corticosteroid medication
* Use of orlistat, phenobarbital, phenytoin, or thiazide
* Morbidly obese (body mass index \> 40 kg/m2)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT04121533
Study Brief:
Protocol Section:
NCT04121533