Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:41 AM
Ignite Modification Date:
2025-12-25 @ 2:41 AM
NCT ID:
NCT06179433
Eligibility Criteria:
Inclusion Criteria:
1. Consenting healthy adults with age range of 18- 40 years
2. Patient presenting with atleast one permanent mandibular molar with necrotic pulp (negative response to sensibility testing by cold and electric pulp test).
3. Radiographic evidence of periapical radiolucency of strictly endodontic origin score ≥3 according to the classification of Ørstavik et al (diagnosis of asymptomatic apical periodontitis or chronic apical abscess) with lesion size ≤ 5mm
Exclusion Criteria:
* Non-restorable teeth or tooth with severe coronal defect where rubber dam isolation is not possible
* Teeth with root fractures or pathological root resorptions
* Teeth with endodontic- periodontal communications
* Patients with generalized chronic periodontitis or periodontal pocket more than 3 mm
* Teeth with previous root canal treatment
* Severe root canal curvatures
* Pregnant or lactating women
* Patients with a history of systemic diseases and/or receiving medications that affect healing or blood coagulation.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
40 Years
Study:
NCT06179433
Study Brief:
Protocol Section:
NCT06179433