Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:40 AM
Ignite Modification Date:
2025-12-25 @ 2:40 AM
NCT ID:
NCT01111734
Eligibility Criteria:
Inclusion Criteria:
All participants:
1. Participants must be aged 13 years to 21 years with the ability to provide consent or guardian consent and assent.
2. They must be available to come to the University of Minnesota for study visits.
All DSH participants:
1\) Must have engaged in DSH at least 4 times, with most recent episode in past three months.
Controls
1. Have no history of deliberate self-harm
2. Have no current or past psychiatric diagnoses
Exclusion Criteria:
1. Those who are pregnant, breastfeeding, or who have a positive urine drug screen will not be included.
2. Individuals with unstable medical illnesses, a history of seizures or heart attack, or arrhythmia not be included.
3. Participants will not have a history of Bipolar type I or II, dementia, schizophrenia or any other psychotic disorder.
4. Patients with active suicidal intent will not be included.
5. If DSH participants are currently taking medications, the doses of these must be stable 1 month prior to study onset.
For Receiving NAC:
1. Participants may not be taking the following medications concurrently, due to the possibility of medication interactions: activated charcoal, ampicillin, carbamazepine, cephaloridine, cloxacillin, methicillin, nitroglycerin, oxacillin, penicillin G, quinacillin.
2. Participants cannot have a history of allergic reaction to NAC.
For MRI Scanning:
1. Participants may not have any metal in their body that would be unsafe in an MRI scanner.
2. Participants with claustrophobia will not be included.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
13 Years
Maximum Age:
21 Years
Study:
NCT01111734
Study Brief:
Protocol Section:
NCT01111734