Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:38 AM
Ignite Modification Date:
2025-12-25 @ 2:38 AM
NCT ID:
NCT03723434
Eligibility Criteria:
Inclusion Criteria:
Inclusion Criteria for Healthy Participants:
* Age from 18 to 85 years
* Right-handed
* Normal hearing and (corrected) vision
* Able to understand and give informed consent
* English speaker
Inclusion Criteria for Patients:
* Age from 18 to 85 years
* Stroke (ischemic subcortical, intermediate level, chronic phase 3 weeks or more from lesion)
* TBI (closed-skull, intermediate level, chronic phase 3 weeks or more from lesion)
* MS (white matter subcortical lesion)
* Clinical and radiological evidence supporting the above diagnoses
* One or more behavioral symptoms possibly linked to the white matter lesion(s)
* Stable medical condition
* English speaker
Exclusion Criteria:
Exclusion Criteria for Healthy Participants:
* Cardiac pacemaker or pacemaker wires; neurostimulators; implanted pumps
* Metal in the body (rods, plates, screws, shrapnel, dentures, IUD) or metallic particles in the eye
* Surgical clips in the head or previous neurosurgery
* Any magnetic particles in the body
* Cochlear implants
* Prosthetic heart valves
* Epilepsy or any other type of seizure history
* Any neurological diagnoses or medications influencing brain function
* History of significant head trauma (i.e., extended loss of consciousness, neurological sequelae)
* Known structural brain lesion
* Significant other disease (heart disease, malignant tumors, mental disorders)
* Significant claustrophobia; Ménière's disease
* Pregnancy (ruled out by urine ß-HCG if answers to screening questions suggest that pregnancy is possible), breast feeding
* Non prescribed drug use
* Failure to perform the behavioral tasks or neuropsychological evaluation tests
* Prisoners
Exclusion Criteria for Patients:
* Same as above, excluding the requirement of no structural brain lesion, and medications influencing brain function are allowed
* Patients with cortical lesions or CSF-filled cysts/cavities near the TMS sites
* MS patients with acute exacerbation
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
85 Years
Study:
NCT03723434
Study Brief:
Protocol Section:
NCT03723434