Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:34 AM
Ignite Modification Date:
2025-12-25 @ 2:34 AM
NCT ID:
NCT02357134
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of cancer, with evidence of primary or secondary lung involvement
* Average dyspnea Borg Scale \>= 4 of 10 with severe exertion over the past week
* Oxygen saturation \> 90% on ambient air at time of assessment
* Able to communicate in English or Spanish
* Karnofsky performance status \>= 50%
* Seen at Supportive Care, cardiopulmonary center, thoracic radiation oncology or thoracic medical oncology
Exclusion Criteria:
* Resting dyspnea modified Borg Scale \> 7 of 10 at enrollment
* Severe obstructive lung disease (forced expiratory volume in 1 second \[FEV1\]/forced vital capacity \[FVC\] \< 70% post bronchodilator and forced expiratory volume in 1 second \< 30% predicted)
* Delirium (i.e., Memorial Delirium Rating Scale \> 13)
* History of unstable angina or myocardial infarction in the last week
* Acute pulmonary embolus or pulmonary infarction in the last week
* Thrombosis of lower extremities in the last week
* Acute myocarditis, pericarditis, or endocarditis in the last week
* Symptomatic aortic stenosis or syncope in the last week
* Suspected dissecting aneurysm
* Severe untreated resting arterial hypertension (\> 200 mmHg systolic, \> 120 mmHg diastolic) at the time of enrollment
* Uncontrolled arrhythmias causing symptoms or hemodynamic compromise in the last week
* Uncontrolled heart failure in the last week
* Pleural effusion requiring thoracentesis within 1 week of study enrollment or scheduled during the study period
* Airway obstruction requiring stenting within 1 week of study enrollment or scheduled during the study period
* Pneumonia requiring antibiotics at the time of study enrollment
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02357134
Study Brief:
Protocol Section:
NCT02357134