Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:33 AM
Ignite Modification Date:
2025-12-25 @ 2:33 AM
NCT ID:
NCT01245634
Eligibility Criteria:
Inclusion Criteria:
* Adult patients, \> 18 and \> 85 years of age
* Patients undergoing primary multi-vessel CABG with at least one saphenous vein graft. with or without cardiopulmonary bypass
* Body mass index (BMI) \</= 35 kg/m2
Exclusion Criteria:
* Participation in previous studies evaluating RO4905417
* Positive for HIV, receiving antiretroviral drugs, or immuno-suppressed
* Acute infection at screening or active chronic infection within 3 months prior to CABG surgery
* Patients undergoing emergency cardiac surgery for an immediately life-threatening condition
* Patients undergoing concomitant valve surgery
* History of CABG (only patients without prior CABG surgery will be admitted to the study)
* Left ventricular ejection fraction \< 20%
* History of transient ischemic attack or stroke within the 12 weeks prior to the CABG procedure
* Significant renal or liver impairment
* Malignancy diagnosed within the previous 5 years (except for successfully resected basal cell cancer)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
85 Years
Study:
NCT01245634
Study Brief:
Protocol Section:
NCT01245634