Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:33 AM
Ignite Modification Date:
2025-12-25 @ 2:33 AM
NCT ID:
NCT00785434
Eligibility Criteria:
Inclusion Criteria:
* written informed consent will be obtained from each patient
* aged 18 to 65 inc
* suffering from MDD as defined by DSM IV
* have been taking citalopram in a dose of at least 20mg for at least six weeks
* an inadequate response -- defined as failure to achieve a MADRS score of \<12
Exclusion Criteria:
* Significant other psychiatric disorder which would interfere with trial assessments. Co-morbid generalized anxiety disorder (GAD) and panic will be permitted where MDD is considered the primary diagnosis .
* history of mania or bipolar disorder
* Known contraindication for the use of citalopram or escitalopram.
* Significant bleeding disorder
* Prominent suicidal ideation (score more than 4 in the MADRS "suicidal thoughts" item)
* Alcohol or substance dependence in the past 6 months
* Major physical illness
* Significant liver or renal function abnormality
* Significant ECG abnormalities
* Pregnant or lactating females
* Inadequate contraception
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT00785434
Study Brief:
Protocol Section:
NCT00785434