Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:25 PM
Ignite Modification Date:
2025-12-24 @ 2:25 PM
NCT ID:
NCT05673759
Eligibility Criteria:
Inclusion Criteria:
For Mild Alzheimer Disease (AD) dementia
* Meets probable AD dementia National Institute on Aging and Alzheimer's Association (NIA-AA) criteria
* 50-90 years old
* Mini-Mental State Examination (MMSE) 20-27
* Performance on delayed recall and recognition memory worse than 1.5 standard deviation (SD) for age and education
* Performance on delayed recall and recognition memory worse than 1.5 SD for age \& education in at least one other cognitive domain (e.g., language, executive functioning) based on other tests in our neuropsychological test battery.
* Dr. Turk and Dr. Budson will confirm all mild AD dementia diagnoses
For Mild cognitive impairment (MCI)
* MCI due to any etiology 50-90 years old
* MMSE \> 23
* Performance on delayed recall and recognition memory worse than 1.0 SD for age \& education adjusted norms
* Dr. Turk and Dr. Budson will confirm all MCI diagnoses
For Healthy older adults
* 50-90 years old
* Functioning normally in occupation determined by self-report
For Healthy younger adults
* 20-50 years old
* Functioning normally in occupation determined by self-report
Exclusion Criteria:
A clinically significant problem of any of the following conditions:
* depression
* heavy alcohol or drug use
* cerebrovascular disease
* a different degenerative disease (e.g., fronto-temporal dementia, Parkinson's disease)
* any medical condition whose severity could significantly impair cognition (e.g., organ failure)
* on any antipsychotic or epilepsy medication
* Unable to understand the consent form
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
20 Years
Maximum Age:
90 Years
Study:
NCT05673759
Study Brief:
Protocol Section:
NCT05673759