Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:26 AM
Ignite Modification Date:
2025-12-25 @ 2:26 AM
NCT ID:
NCT01148134
Eligibility Criteria:
Inclusion Criteria:
* Age \>/= 18 years
* New Diagnosis of Bcr-Abl positive ALL or Bcr-Abl negative ALL
* Receiving induction chemotherapy with the standard Princess Margaret Hospital modified DFCI protocol
* Will have a functioning central venous access catheter in-situ
* Agreeing to participate in the study and sign the informed consent form
Exclusion Criteria:
* Concomitant use of other agents that inhibit hepatic cytochrome CYP3A4, as these drugs may alter vincristine and imatinib levels
* Elevated liver function tests: bilirubin \>1.5xULN or AST/ALT \>2.5xULN, or documented history of chronic liver disease.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01148134
Study Brief:
Protocol Section:
NCT01148134