Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:24 AM
Ignite Modification Date:
2025-12-25 @ 2:24 AM
NCT ID:
NCT01969734
Eligibility Criteria:
Inclusion Criteria:
* Adult patients with stable moderate COPD (FEV1 45-80%pred)
* Emphysema on CT with a defined target lobe
* CT thorax must demonstrate intact interlobar fissures adjacent to the target lobe
* Hyperinflation - TLC ≥100% predicted, RV ≥150% predicted
* Exertional breathlessness with MRC dyspnoea score ≥3
* Optimum COPD treatment for at least 6 weeks
* No COPD exacerbation for at least 6 weeks
* Fewer than 3 admissions for infective exacerbations in the preceding 12 months
* Six minute walk distance of \<450m
Exclusion Criteria:
* Inability to obtain informed consent
* Significant co morbidity which limits exercise capacity or prognosis
* Co-morbidities that would render bronchoscopy or sedation unsafe
* Clinically significant bronchiectasis
* Lung nodule requiring further investigation or treatment
* Subject taking clopidogrel, warfarin, or other anticoagulants and unable to abstain for 5 days pre-procedure
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01969734
Study Brief:
Protocol Section:
NCT01969734