Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:24 AM
Ignite Modification Date:
2025-12-25 @ 2:24 AM
NCT ID:
NCT06368934
Eligibility Criteria:
Inclusion Criteria:
1. Eligible patients are aged between 18 and 80, have newly diagnosed high-grade diffuse adult-type gliomas, and have not received any other treatment besides puncture biopsy.
2. Preoperative KPS score ≥70.
3. Enhanced MRI can be tolerated.
4. Sign the informed consent form.
5. Patients with supratentorial gliomas and lesions confined to the unilateral frontal, temporal, parietal, and occipital lobes are included.
6. Imaging total resection can be completed after preoperative imaging evaluation.
7. The intraoperative integrative diagnosis was IDH wild-type high-grade glioma with TERT promoter mutation.
Exclusion Criteria:
1. The tumor involves the anterior central gyrus, posterior central gyrus, nigral gyrus, limbic lobe, corpus callosum, basal ganglia, and lateral ventricles.
2. The tumor involves 2 or more lobes of the brain;
3. Developing severe systemic diseases such as renal insufficiency, hepatic insufficiency, cardiac insufficiency, etc.
4. Previously, the patient had experienced other types of malignant tumours.
5. Developing other brain diseases, such as Parkinson's or Alzheimer's disease.
6. Simultaneously participating in other clinical trials.
7. Expected survival is less than 3 months.
8. Not receiving Stupp protocol after surgery.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT06368934
Study Brief:
Protocol Section:
NCT06368934