Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:24 AM
Ignite Modification Date:
2025-12-25 @ 2:24 AM
NCT ID:
NCT00278434
Eligibility Criteria:
DISEASE CHARACTERISTICS:
* Biopsy confirmed cervical intraepithelial neoplasia (CIN) 2/3 or 3
* Planning loop excision or cone biopsy
* Diagnosis within 2 months prior to study entry
* Standard histological grading according to Richart
* Visible lesion by colposcopy
* No unsatisfactory colposcopy or lesions extending into the endocervical canal that cannot be visualized entirely by colposcopy
* No suspicion of invasive cervical cancer by cytology, histology or colposcopy
* No cytologic evidence of glandular atypia or dysplasia
PATIENT CHARACTERISTICS:
* Creatinine normal
* Screening laboratory values within normal range (e.g., complete blood count, liver function tests, renal panel, and electrolytes)
* Not pregnant or nursing
* Negative pregnancy test
* Fertile patients must use effective contraception
* Able to read and speak English or Spanish
* No known hypersensitivity to bisphosphonates
* Not immunocompromised
* No known HIV positivity
* No aspirin-sensitive asthma due to association of bisphosphonates with bronchoconstriction
* No unexplained abnormal vaginal bleeding
PRIOR CONCURRENT THERAPY:
* No concurrent loop diuretics, aminoglycosides, other nephrotoxic drugs, immunosuppressive drugs, or other investigational agents
Healthy Volunteers:
False
Sex:
FEMALE
Minimum Age:
18 Years
Maximum Age:
120 Years
Study:
NCT00278434
Study Brief:
Protocol Section:
NCT00278434