Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:23 PM
Ignite Modification Date:
2025-12-24 @ 2:23 PM
NCT ID:
NCT05181059
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of histopathologically proven locoregional advanced primary breast cancer:
1. Tumors \> 5 cm (= T3) or
2. Tumors with invasion of the skin or chest wall (= T4) or
3. Any tumor with ≥ 4 axillary lymph nodes or ipsilateral internal mammary, infraclavicular or supraclavicular nodal involvement (= N2-3)
* Heterogeneously or extremely dense breasts as described by visual assessment on full-field digital mammograms: category C or D according to the ACR BI-RADS lexicon
Exclusion Criteria:
* History of allergic reactions to iodinated contrast agents
* Pregnancy or breast feeding
* Treatment of thyroid disease with radioactive iodine
* Use of metformin
* Creatinine clearance \< 45 ml/min
* Chronic or acutely worsening renal disease
* Patients who are declared incompetent
Sex:
FEMALE
Minimum Age:
18 Years
Study:
NCT05181059
Study Brief:
Protocol Section:
NCT05181059