Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:19 AM
Ignite Modification Date:
2025-12-25 @ 2:19 AM
NCT ID:
NCT05981534
Eligibility Criteria:
Inclusion Criteria:
* Male and female patients aged over 50 with end-stage knee OA
* Patient are on the waiting list for TKR at Prince of Wales Hospital
* Walk unaided for 6 meters
* Able to comply with the assessments and has given oral and written consent
* Patients with vitamin D insufficiency and deficiency at the baseline measurement (25(OH)D \<30 ng/mL)
Exclusion Criteria:
* Patients with connective tissue disorders or myositis condition
* History of any Hip \& Knee surgery
* Patients with malnutrition were assessed by Mini-Nutritional assessment.
* Patients with acute immobility (i.e., post-hip fracture or post-acute hospital admission)
* Patient scheduled for TKR within six months
* Patients already taking vitamin D supplements
* Patients with a known contraindication to vitamin D treatment (such as allergy)
* Patients who have renal impairment with glomerular filtration rate (eGFR) \< 30 ml/minute
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Study:
NCT05981534
Study Brief:
Protocol Section:
NCT05981534