Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:17 AM
Ignite Modification Date:
2025-12-25 @ 2:17 AM
NCT ID:
NCT01837160
Eligibility Criteria:
Inclusion Criteria
* asymptomatic mild (peak valve velocity of 2-5-3.0 m/s; n=10), moderate (peak valve velocity of 3.0-4.0 m/s; n=10) or severe aortic stenosis (peak valve velocity of \>4.0 m/s; n=10) and 10 patients with severe aortic stenosis proceeding to aortic valve replacement.
* Healthy control subjects (n=10) will have no past medical history of ischaemic heart disease or valvular heart disease and have a structurally normal heart on echocardiography.
Exclusion Criteria:
* Atrial fibrillation
* Hepatic failure (Childs-Pugh grade B or C)
* Renal failure (estimated glomerular filtration rate \<25 mL/min)
* Women of child-bearing potential
* Contraindication to magnetic resonance imaging
* Inability to undergo scanning
* Ochronosis and those with any form of collagen-vascular disease.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
40 Years
Study:
NCT01837160
Study Brief:
Protocol Section:
NCT01837160