Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:16 AM
Ignite Modification Date:
2025-12-25 @ 2:16 AM
NCT ID:
NCT01035060
Eligibility Criteria:
Inclusion Criteria:
* Men and women aged 18-30 years
* Men and women aged \> 70 years
* Body mass index \< 35
* Willing and able to participate in all aspects of the study
* Sedentary to moderately active lifestyle \<120 min physical activity/week \< 30 min moderate aerobic exercise/week \< 30 min resistance training/week OR Participates in regular structured exercise \> 120 min/week
* Non-smoking
Exclusion Criteria:
* Active treatment for cancer, stroke (\< 6 mo), peripheral vascular disease, coronary artery disease (myocardial infarction \<6 mo), state III, IV Congestive Heart Failure, valvular heart disease, major psychiatric disease, severe anemia, liver or renal disease, diabetes, severe osteoarthritis, blindness or deafness, fracture in upper or lower extremity within the last 6 months, upper or lower extremity amputation, anticoagulant therapy (aspirin use is permitted), parkinsons disease
* Failure to give consent
* Anabolic medications (growth hormone or testosterone)
* High amounts of physical activity (i.e. running, bicycling etc \> 120 min/week).
* Dementing illness
* Smoking
* Pregnant
* Significant cognitive impairment; Mini-Mental State (MMSE) exam \< 24
* Statin Usage
* Excessive alcohol use (\>2 drinks per day)
* Resting heart rate \> 120 bpm
* Systolic blood pressure \> 180 mmHg
* Diastolic blood pressure \> 110 mmHg
* History of significant head injury
* Anticholinesterase inhibitor (such as Aricept)
* Contraindications to MRI (e.g. cardiac pacemaker, implanted cardiac defibrillator, aneurysm clip, claustrophobia, etc.)
* Current Use of Antidepressant Medications
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01035060
Study Brief:
Protocol Section:
NCT01035060