Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:16 AM
Ignite Modification Date:
2025-12-25 @ 2:16 AM
NCT ID:
NCT02905760
Eligibility Criteria:
Inclusion Criteria
* Age \>18 years
* Inferior acute myocardial infarction (≤J + 7)
* Right ventricular extension defined by one following echocardiographic criteria:
* Dilatation of the right ventricle (RV/LV area\> 0.9)
* RV dysfunction defined by TAPSE \<16mm or S velocity \<10cm.s-1
* Akinesia or hypokinesia of two contiguous segments of the right ventricle
* Decrease of pitch on lung failure flow \<150ms
* Inferior vena cava dilatation (≥20mm) and non-compliant (changes \<50%) associated with one hemodynamic instability criteria:
* Oliguria (diuresis \<800mL/24h or 0.5mL/kg/min)
* Systolic blood pressure \<100mmHg
* Oxygen saturation \<91% on room air
* Bradycardia (heart rate \<60/min, not valid for patients on beta-blockers).
* Informed consent for study participation signed.
Exclusion Criteria
* Minor and pregnant woman
* Mechanical complications of myocardial infarct
* Patients who received\> 40mg diuretic /day during the last 15 days
* Hypersensitivity to furosemide or any of its excipients
* Aortic stenosis (area \<1 cm² or mean gradient\> 40mmHg), mitral or aortic regurgitation grade ≥3
* Catecholamine support for left ventricular failure with left ventricular ejection fraction \<35%
* Renal impairment defined by a serum creatinine\> 200μmol / mL
* Sodium and water retention
* Urinary tract obstruction
* Hypovolemia or dehydration
* Severe hypokalemia (K + \<3 mmol / L)
* Severe hyponatremia (Na + \<125 mmol / L)
* Hepatitis ongoing, liver failure or hepatic encephalopathy
* No affiliation to a social security scheme or other social protection scheme
* Private Patient of liberty or under legal protection (guardianship)
* Inability or refusal to understand or refusal to sign the informed consent from study participation
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02905760
Study Brief:
Protocol Section:
NCT02905760