Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:15 AM
Ignite Modification Date:
2025-12-25 @ 2:15 AM
NCT ID:
NCT00704860
Eligibility Criteria:
Inclusion Criteria:
* Male or female between ages of 18 to 65 years of age.
* A diagnosis of Major Depression according to the DSM-IV criteria
* Failing to achieve remission while receiving at least two different antidepressants at adequate dosage for at least 6 weeks.
* Initial score of at least 18 on the HAMD-17 item rating scale
Exclusion Criteria:
* A diagnosis of substance abuse or dependence in the last 6 months or a lifetime diagnosis of substance abuse according to the DSM-IV criteria, elicited by inquiry.
* A diagnosis of post-traumatic stress disorder, schizophrenia, schizo-affective disorder and other psychotic disorders, anorexia nervosa or a history of a manic or mixed episode
* Major medical illnesses including endocrine and neurological disorders, as well as a history of significant head trauma
* Exposure to oral or intravenous steroids
* Contraindications to magnetic resonance imaging
* An IQ less than 80
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT00704860
Study Brief:
Protocol Section:
NCT00704860