Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:11 AM
Ignite Modification Date:
2025-12-25 @ 2:11 AM
NCT ID:
NCT00238160
Eligibility Criteria:
DISEASE CHARACTERISTICS:
* Histologically confirmed hepatocellular carcinoma (HCC) with portal vein tumor thrombus
* Tumor thrombus in the main trunk or first branch of the portal vein
* No apparent distant metastases on chest CT scan and bone scintigraphy within the past 6 weeks
* No pleural effusion or ascites
PATIENT CHARACTERISTICS:
Age
* Not specified
Performance status
* ECOG 0-1
Life expectancy
* Not specified
Hematopoietic
* Neutrophil count \> 1,000/mm\^3
* Platelet count \> 50,000/mm\^3
* Hemoglobin \> 8 g/dL
Hepatic
* Bilirubin \< 2 times upper limit of normal (ULN)
* ALT and AST \< 4 times ULN
Renal
* Creatinine normal
Cardiovascular
* No severe heart disease
* No cardiac effusion
Other
* No other malignant disease
* No high risk for esophageal varices rupture
* No allergy to fluorouracil or cisplatin
PRIOR CONCURRENT THERAPY:
Biologic therapy
* Not specified
Chemotherapy
* No prior hepatic arterial chemotherapy
* No prior systemic chemotherapy for HCC
Endocrine therapy
* Not specified
Radiotherapy
* Not specified
Surgery
* Not specified
Healthy Volunteers:
False
Sex:
ALL
Study:
NCT00238160
Study Brief:
Protocol Section:
NCT00238160