Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:11 AM
Ignite Modification Date:
2025-12-25 @ 2:11 AM
NCT ID:
NCT01661660
Eligibility Criteria:
Subjects control Inclusion criteria
* Male or Female ≥ 65 years
* Subjects were not accompanied by an Alzheimer subject recruited for the study;
* Subjects showing no locomotor disability;
* Subjects with no cognitive impairment overall with a score\> 27 on the MMSE.
Special cases:
people with no schooling aged 50 to 79 years we take a MMSE\> 22/30 and for over 80 years a MMSE\> 21/30 - by the standards of Kalafat, 2003) (Folstein, Folstein et al. 1975), or arguments in favor of the following diagnosis: probable Alzheimer's disease according to the criteria of the NINCDS-ADRDA and / or major depressive episode according to DSM-IV-R;
* Subjects receiving a social security system;
* Signature of informed consent.
Exclusion Criteria
* Failure to perform the protocol due to a mobility impairment;
* Prescription of a new psychotropic medication (hypnotic, anxiolytic, antidepressant, antipsychotic) in the week preceding the assessment;
* Patients implanted with a pacemaker;
* Patient Trust under curatorship or judicial protection;
* Detainees (administrative or judicial).
Predementia / MCI Patients Inclusion criteria
* Men or women ≥ 65 years.
* Subjects with a diagnosis of MCI according to the criteria of the National Institute on Ageing and Alzheimer's Association group (Albert MS, 2011, see Appendix B), or Alzheimer's disease stage prédementiel (B. Dubois, 2010; see Appendix C)
* Subjects with a score of 0 to items of "tremors" and "muscle stiffness" of the UPDRS III
* Subjects with no criteria for major depressive episode according to DSM IV-R;
* Subjects receiving a social security system;
* Signature of informed consent. Exclusion Criteria
* Failure to pass neuropsychological testing because of a sensory or motor deficit;
* Prescription of a new psychotropic medication (hypnotic, anxiolytic, antidepressant, antipsychotic) in the week preceding the assessment;
* Patients implanted with a pacemaker;
* Patient Trust under curatorship or judicial protection.
dementia subjects Inclusion criteria
* Men and women older than 65 years
* Subjects with a diagnosis of Alzheimer's disease according to NINCDS-ADRDA (McKhann, Drachman et al. 1984) or Alzheimer's typical or atypical (B. Dubois et al. 2007)
* MMSE score ≥ 16
* Subjects with a score of 0 to items of "tremors" and "muscle stiffness" of the UPDRS III
* Subjects with no criteria for major depressive episode according to DSM IV-R;
* Subjects receiving drug treatment by acetylcholinesterase inhibitor or memantine in standard dose and stable for at least 3 months;
* Subjects receiving a social security system;
* Signature of informed consent.
Exclusion Criteria
* Failure to pass neuropsychological testing because of a sensory or motor deficit;
* Prescription of psychotropic medication (hypnotic, anxiolytic, antidepressant, antipsychotic) in the week preceding the assessment;
* Patients implanted with a pacemaker
* Patient Trust under curatorship or judicial protection.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
65 Years
Study:
NCT01661660
Study Brief:
Protocol Section:
NCT01661660