Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:09 AM
Ignite Modification Date:
2025-12-25 @ 2:09 AM
NCT ID:
NCT03560960
Eligibility Criteria:
Inclusion Criteria:
* Current research subjects at the BU , Memory Center VA Boston Healthcare, or Indiana University Alzheimer Disease Center
* A consensus diagnosis of probable Alzheimer's Disease (AD), amnestic mild cognitive impairment (MCI), or control
* BMI of 20-35
* Probable AD subjects must be confirmed for positive AD pathology in the central nervous center (CNS0
* Probable AD subjects must have a designated research proxy signed before they became demented.
Exclusion Criteria:
* Diabetes mellitus
* Gastroparesis
* Use of insulin, pramlintide, other injectable anti-hyperglycemic agents, such as glucagon like peptide-1 (GLP-1), or oral anti-diabetic products
* Unexplained hypoglycemia (glucose ≤ 60 mg/dL) or hyperglycemia (glucose ≥ 126 mg/dL) pre-injection
* History of stroke
* Seizures or use of anti-seizure medications
* History of brain injury and loss of consciousness
* Diagnosed cerebral amyloid angiopathy (CAA)
* Infection within 1 month
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
60 Years
Maximum Age:
90 Years
Study:
NCT03560960
Study Brief:
Protocol Section:
NCT03560960