Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:09 AM
Ignite Modification Date:
2025-12-25 @ 2:09 AM
NCT ID:
NCT05049460
Eligibility Criteria:
Inclusion Criteria:
* Patients enrolled in the SMART Clinic at University of Kentucky
* 18-60 years of age
* Preferably right hand dominant
* Currently self-report smoking 10 of more cigarettes per day or a score of \> 5 on the Fagerstrom Test for Nicotine
* Willing and able to abstain from all drug use
* Exhaled breath on day of study CO \< 10 ppm
* Stabilized on maintenance buprenorphine if having comorbid opioid use disorder
* Able to read and speak English
* Able to provide informed consent to participate.
Exclusion Criteria:
* Pregnant, nursing, or becoming pregnant during the study.
* History of traumatic brain injury or seizures which are contraindications for transcranial magnetic stimulation (TMS).
* Increased risk of seizure for any reason, including prior diagnosis of epilepsy, seizure disorder, increased intracranial pressure, or history of significant head trauma with loss of consciousness for ≥ 5 minutes which are all contraindications for TMS.
* Presence of intracranial implants (e.g. aneurysms clips, shunts, stimulators, cochlear implants, or electrodes), cardiac pacemakers, or vagus nerve stimulation device which are all contraindications for magnetic resonance imaging.
* Neurological disorder including, but not limited to: space occupying brain lesion; any history of seizures, history of cerebrovascular accident; fainting, cerebral aneurysm, major neurocognitive disorder, Huntington chorea; multiple sclerosis which are all contraindications for TMS.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT05049460
Study Brief:
Protocol Section:
NCT05049460