Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:09 AM
Ignite Modification Date:
2025-12-25 @ 2:09 AM
NCT ID:
NCT06778460
Eligibility Criteria:
Inclusion Criteria:
1. Aged 18-75 years;
2. Scheduled for elective hepatectomy;
3. ASA grade I-III.
Exclusion Criteria:
1. Patients who have been intubated in the ICU following surgery and do not have a planned extubation within 6 hours postoperatively.
2. Patients with a body weight less than 40 kg or greater than 100 kg.
3. Patients with cardiac conduction system abnormalities (second- or third-degree atrioventricular block) or cardiac insufficiency (left ventricular ejection fraction \< 50%).
4. Patients with severe hepatic insufficiency (alanine aminotransferase \[ALT\], aspartate aminotransferase \[AST\], or bilirubin levels more than 2.5 times the upper limit of normal) or renal insufficiency (creatinine clearance rate \< 60 mL/min).
5. Patients with a known hypersensitivity to the investigational drug.
6. Patients with a history of long-term opioid abuse.
7. Patients who are unable to communicate effectively.
8. Patients with serious comorbid medical conditions, such as uncontrolled hypertension, coronary heart disease, intracranial vascular malformations, or acute asthma exacerbations.
9. Patients with a history of epilepsy or a history of manic episodes.
10. Pregnant or breastfeeding women.
11. Patients with glaucoma.
12. Patients with preoperative cognitive dysfunction, bipolar disorder, or other psychiatric disorders, including mental retardation.
13. Patients with primary liver cancer in conjunction with malignant tumors of other organs (such as lung, kidney, intestine, etc.), or those with clinical symptoms or imaging findings suggestive of distant metastasis.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT06778460
Study Brief:
Protocol Section:
NCT06778460