Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:07 AM
Ignite Modification Date:
2025-12-25 @ 2:07 AM
NCT ID:
NCT03780660
Eligibility Criteria:
Inclusion Criteria
* Spontaneous breathing without mechanical assistance
* Central venous catheter (superior vena cava) and monitoring of central venous pressure
* Urinary catheter and monitoring of intra-abdominal pressure
Exclusion Criteria:
* Intolerance to ventilatory manœuvre including Severe basal dyspnea/Symptomatic heart failure (pulmonary edema)
* Contraindication to passive leg raising (intracranial hypertension)
* Passive leg raising unsuitable for measuring hemodynamic response : High grade aortic insufficiency/ Poor echogenicity unsuitable to measure the velocity-time /integral of aortic blood flow/ Pregnancy/Abdominal hypertension with abdominal compartment syndrome/ Lower leg amputation
* Necessity of urgent hemodynamic therapy (within 90 min)
* Modification of hemodynamic therapy during study protocol (vascular filling, increase catecholamine dose
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03780660
Study Brief:
Protocol Section:
NCT03780660