Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:07 AM
Ignite Modification Date:
2025-12-25 @ 2:07 AM
NCT ID:
NCT06937060
Eligibility Criteria:
Inclusion Criteria:
* a clinical diagnosed Psoriatic disease of at least 6 months before signing of informed consent.
* Women who are sexually active and not postmenopausal, agreement to remain abstinent or use 2 effective methods of contraception
* \>18 years of age, up to 75 years of age
* Adult with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)
* Moderate to severe psoriasis (PASI score 5-10= moderate, \>10 = severe)
* Chinese ethnicity
* On stable dose of standard treatment
* Ability to comply with stud
Exclusion Criteria:
* Patients who refuse to give consent
* Contraindication to use of GLP1 RA
* History of pancreatitis
* History of MEN / MTC
* Known hypersensitivity to semaglutide or excipients in semaglutide
* Type 1 diabetes
* Gallbladder disease
* Active malignancy or History of malignancy within 5 years
* Active chronic or acute infection requiring treatment with systemic antibiotics, antiviral, antiparasitic, antiprotozoal, or antifungals within 4 weeks before baseline visit
* Pregnancy or breastfeeding, subjects should inform their healthcare provider of a known or suspected pregnancy
* History of allergic reaction assessed as related to investigational product by the investigator
* Major psychiatric illness
* Treatment with live/ attenuated vaccine within the last 28 days prior to randomisation
* History of alcohol or substance abuse within 6 months prior to initial screening
* Patients with a history of suicidal attempts or active suicidal ideation
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT06937060
Study Brief:
Protocol Section:
NCT06937060