Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:06 AM
Ignite Modification Date:
2025-12-25 @ 2:06 AM
NCT ID:
NCT01508260
Eligibility Criteria:
Inclusion Criteria:
1. All patients must be 18 years of age or older and have a diagnosis of leukemia and be hospitalized on leukemia floor or MICU
2. Weight gain of 10 pounds or more.
3. In addition, patients should have 2 or more signs and symptoms of fluid overload such as: dyspnea, orthopnea, paroxysmal nocturnal dyspnea (PND), peripheral edema, rales, jugular venous distension (JVD), hypoxia (pulse ox \< 90% on room air) and pulmonary edema by chest X-ray.
4. AND be poorly responsive to diuretics defined as positive fluid balance or \< 1% decrease in current body weight / 24 hours with use of furosemide 60 mg IV/24h.
5. Subjects will be eligible regardless of poor performance, organ dysfunctions, organ failures, or other criteria of decompensation and/or debilitation.
6. Subjects will be eligible regardless of platelet counts.
7. Patients may be on a regular floor or in the intensive care unit.
8. They may be on respiratory mechanical ventilation or not.
Exclusion Criteria:
1. Indication for dialysis (as judged necessary by nephrology (hyperkalemia, acidosis).
2. AKI defined as 100% increase in baseline creatinine.
3. Hypotension (SBP \< 90mmHg).
4. Pregnant or breastfeeding women are excluded.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01508260
Study Brief:
Protocol Section:
NCT01508260