Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:06 AM
Ignite Modification Date:
2025-12-25 @ 2:06 AM
NCT ID:
NCT06914960
Eligibility Criteria:
Inclusion Criteria:
* Age between 30-75
* Chronic knee pain that lasts at least 6 months
* Radiographic confirmation of osteoarthritis: Presence of Grade 3 or 4 radiographic changes characterized by significant narrowing in the medial space of the tibiofemoral joint according to the Kellgren-Lawrence classification system
* Knee pain \>40 mm when performing one of the two movements that cause the most severe pain (sitting to standing or going up and down stairs) according to 100 mm VAS
* 50% reduction in VAS with diagnostic genicular nerve block
Exclusion Criteria:
* Presence of systemic inflammatory disease such as rheumatoid arthritis
* Previous RFA treatment to the knee or hyaluronic acid or steroid injection to the knee within the last 3 months
* History of previous knee surgery
* Clinically significant structural abnormalities other than osteoarthritis that may lead to chronic knee pain
* Having undergone physical therapy to the knee in the last 6 months or a history of knee trauma
* Application of other pain treatments
* Body-Mass İndex \<18 and \>40 kg/m2
* Pregnancy
* Presence of uncontrolled serious illness (cancer, diabetes, etc.), infection, psychiatric disorder, coagulation disorder
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
30 Years
Maximum Age:
75 Years
Study:
NCT06914960
Study Brief:
Protocol Section:
NCT06914960