Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:04 AM
Ignite Modification Date:
2025-12-25 @ 2:04 AM
NCT ID:
NCT04032860
Eligibility Criteria:
Inclusion Criteria:
1. older than 18 years and less than 69 years old;
2. HBsAg positive HCV antibody negative and HIV antibody negative;
3. HBV-DNA\>200 IU/mL;
4. BCLC（Barcelona Clinic Liver Cancer） staging O and A stage;
5. Platelet100×10\^9/L;
6. Liver function Child-Pugh A,with no invasion in portal vein, hepatic vein and two large branches, no extrahepatic metastasis;
7. Creatinine clearance rate≥ 70 mL/min;
8. Antiviral treatment was not performed before surgery or antiviral treatment was accepted in a short term (\<3 months);
9. No treatment was performed before the operation. The results of postoperatively histopathological biopsy were HCC;
10. The patients agree to participate in the clinical trial.
Exclusion Criteria:
1. The image found extrahepatic lymph nodes or visceral metastasis, the existence of large vascular invasion, the existence of bile duct embolus in the first operation;
2. The patient combined with a malignant tumor of other organs or had a history of other malignant tumors in other organs;
3. Liver function decompensation, such as: upper gastrointestinal bleeding, refractory ascites, coagulation dysfunction and so on;
4. contraindications to surgery;
5. Patients with poor compliance and not adhered to the follow-ups;
6. Patients refused to participate in the clinical trial.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
69 Years
Study:
NCT04032860
Study Brief:
Protocol Section:
NCT04032860