Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:03 AM
Ignite Modification Date:
2025-12-25 @ 2:03 AM
NCT ID:
NCT04543760
Eligibility Criteria:
Inclusion Criteria:
* Aged ≥ 18 years,
* Admitted to ICU within 72 hours,
* Having confirmed or highly suspected COVID-19 infection (positive RT-PCR and/or computed tomography),
* Having acute hypoxemic respiratory failure with a \[PaO2/FiO2\] ratio between 100 mmHg and 300 mmHg,
* Having given free and informed written consent,
* Being affiliated with or benefiting from a social security scheme.
Exclusion Criteria:
* Unable to achieve a prone position for mobility reasons,
* Unable to achieve a prone position due to agitation whatever the cause,
* With clinical occlusive syndrome in order to limit the risk of inhalation,
* Having a contraindication to the use of the esophageal catheter,
* Having signs of respiratory distress or disturbance of consciousness requiring intubation within the next hours,
* Having hypercapnia indicating the use of non-invasive ventilation (PaO2\> 50 mmHg),
* Having severe hypoxemia defined by PaO2 / FiO2 \<100mmHg,
* Ongoing pregnancy or breastfeeding,
* Subject to a measure for the protection of justice.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04543760
Study Brief:
Protocol Section:
NCT04543760