Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:03 AM
Ignite Modification Date:
2025-12-25 @ 2:03 AM
NCT ID:
NCT07128160
Eligibility Criteria:
Inclusion Criteria:
1. Age 18 years or older.
2. Diagnosis of RRMS based on the 2017 McDonald Criteria.
3. Expanded Disability Status Scale (EDSS) score ≤ 6.5.
4. On a stable dose of disease-modifying therapy (DMT) for at least 3 months or naeive patients not use DMT before
5. Free of relapses or steroids treatment (at least 3 months after a relapse or corticosteroid therapy)
6. Ability to give informed consent and complete neuropsychological assessments.
Exclusion Criteria:
1. Presence of other neurological or psychiatric disorders (e.g., major depression, bipolar disorder, schizophrenia).
2. History of alcohol or substance abuse.
3. Contraindications to MRI (e.g., pacemakers, metallic implants) and TMS (i.e., history of seizures, presence of ferromagnetic implants in the head area).
4. Medications known to alter the corticospinal excitability.
5. Severe visual deficit, motor weakness, or intellectual impairment (as per the Mini-Mental State Exam score \< 24).
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07128160
Study Brief:
Protocol Section:
NCT07128160