Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:02 AM
Ignite Modification Date:
2025-12-25 @ 2:02 AM
NCT ID:
NCT03727360
Eligibility Criteria:
Inclusion Criteria:
* 60 to 80 years old
* Fluent in English
* Willingness to make the time commitment to participate in the project, including randomization to treatments
* Physically inactive (physical activity not more than 2 days per week for the past 6 months)
* Physician consent to undergo an exercise stress test and engage in moderate intensity exercise
* Determined to be safe for MRI
Exclusion Criteria:
* Neurological illnesses/conditions such as cerebral palsy, epi¬lepsy, brain tumor, chronic meningitis, multiple scle¬rosis, pernicious anemia, normal-pressure hydrocephalus, HIV infection, Parkinson's disease, and Huntington's disease
* Untreated hypertension, glaucoma, and chronic obstructive pul¬monary disease
* Untreated severe major depression
* Substance abuse or dependence
* Current use of psychoactive medications, except selective serotonin/norepinephrine reuptake inhibitor antidepressants
* Use of acetylcholinesterase inhibitors (e.g., Aricept)
* Unstable or severe cardiovascular disease or asthmatic condition
* History of transient ischemic attack, cerebral ischemia, or clinically diagnosed stroke
* Diagnosis of mild cognitive impairment or dementia, or objective evidence of cognitive impairment
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
60 Years
Maximum Age:
80 Years
Study:
NCT03727360
Study Brief:
Protocol Section:
NCT03727360