Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:00 AM
Ignite Modification Date:
2025-12-25 @ 2:00 AM
NCT ID:
NCT06031194
Eligibility Criteria:
Inclusion Criteria:
* \* Adult (age ≥ 18 years at diagnosis)
* Diagnosis of DLBCL or PCNSL
* Planned to undergo treatment with HDMTX (≥ 3 g/m\^2) at the James Cancer Hospital.
Note: patients with CKD are eligible to participate regardless of eGFR provided the treating physician is planning a dose of HDMTX of at least 3 g/ m\^2.
* Ability to provide informed consent.
Exclusion Criteria:
* \* Patients with a "currently active" second malignancy that, in the opinion of the principal investigator, will interfere with patient participation, or confound data interpretation
* Pregnancy (positive serum or urine pregnancy test), lactating or breast feeding
* Prisoners or incarcerated patients
* Total bilirubin \> 5 mg/dL
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06031194
Study Brief:
Protocol Section:
NCT06031194