Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:00 AM
Ignite Modification Date:
2025-12-25 @ 2:00 AM
NCT ID:
NCT01108094
Eligibility Criteria:
INCLUSION CRITERIA
* At least one BCC tumor (greater than 4 mm in diameter) at any skin location, to be biopsied and surgically removed.
* Had at least one liver function test \[eg, aspartate aminotransferase (AST), alanine aminotransferase (ALT)\] with normal results in the last year.
* Consent to research use of their BCC tissue.
* Cohort A or B: Willing to take itraconazole during the 2 to 3 weeks between biopsy and surgical removal of BCC
EXCLUSION CRITERIA
* History or current hepatitis or other liver disease.
* Currently taking systemic medications that would affect BCC tumors (oral retinoids) or metabolism of itraconazole (anti-convulsants, corticosteroids)
* History or current evidence of malabsorption or liver disease within the one year prior to enrollment.
* History or current evidence of hyperthyroidism increasing metabolism of itraconazole
* Unable to attend to 2nd study visit at Stanford for Mohs surgical excision
* Current immunosuppression disease (cancer, autoimmune disease)
* Receiving immunosuppressive drugs
* Pregnant
* Lactating
* Any female actively trying to become pregnant
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01108094
Study Brief:
Protocol Section:
NCT01108094