Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:47 AM
Ignite Modification Date:
2025-12-25 @ 1:47 AM
NCT ID:
NCT00747994
Eligibility Criteria:
Inclusion Criteria:
* Patient aged over 18 years,
* patient who underwent a clinical examination,
* patient who gave its written consent,
1. Each individual (index case) affected by Paget's disease of bone (with diagnosis confirmed by alkalies phosphatases analysis and/or imaging with bone scintigraphy and radiographies on the affected sites with a typical aspect of the disease), and :
* At least one relative affected by Paget's disease of bone with confirmed diagnosis (see above),
* Or an age at diagnosis \< 55 years,
* Or a polyostotic involvement with at least 4 affected bones,
* Or the presence of a bone deformity at the time of the diagnosis.
2. Each relative with established phenotype by imaging (bone scintigraphy and/or radiographies), at first or second degree of relativeness of an index case defined in (a).
Exclusion Criteria:
* Index case with not confirmed Paget's disease of bone by biological and/or radiological examinations,
* Index with confirmed Paget's disease but without relative with the same disease, with an age at diagnosis \>55 years, with a number of affected bones \<4, without any bone deformity at the time of the diagnosis
* Healthy relatives of a Paget patient who refuse to undergo bone scintigraphy and bone radiographies.
* Individuals \< 18 years
* Pregnant or breast
* feeding woman-individual living ina sanitary or social establishment
* individual under guardianship
* individual in an emergency situation
* individual unable to give his consent
* incarcerated individual
* patient not covered by healthcare institutions
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00747994
Study Brief:
Protocol Section:
NCT00747994