Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:46 AM
Ignite Modification Date:
2025-12-25 @ 1:46 AM
NCT ID:
NCT01734694
Eligibility Criteria:
Inclusion Criteria:
* Aged 18 years or older
* Receiving intravenous vancomycin for the treatment of healthcare associated pneumonia, osteomyelitis/septic arthritis, endocarditis/bacteremia, or acute bacterial skin and skin structure infections
* Expected to receive vancomycin for at least 72 hours and are within the first 72 hours of therapy
* Have at least two or more of the following risk factors for drug-induced nephrotoxicity: a) receipt high-dose vancomycin therapy (greater than or equal to four grams per day) b) receipt of vasopressors c) receipt of nephrotoxic drugs (i.e. aminoglycosides, furosemide, acyclovir, amphotericin b, colistin, and intravenous contrast dye) d) pre-existing renal dysfunction (i.e. SCr greater than or equal to 1.5 mg/dL).
Exclusion Criteria:
* Pregnancy
* End-stage renal disease
* Receipt of more than 4 grams of vancomycin prior to enrollment on current admission
* Absolute neutrophil count \< 1000/mm3
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01734694
Study Brief:
Protocol Section:
NCT01734694