Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:46 AM
Ignite Modification Date:
2025-12-25 @ 1:46 AM
NCT ID:
NCT06250894
Eligibility Criteria:
Inclusion Criteria:
* Age 18-70, male and female.
* Histologically confirmed locally advanced esophagogastric junction Adenocarcinoma cT3-4aNxM0 (AJCC v8), Siewert typed as type II-III.
* No previous anti-tumor treatment.
* ECOG score was 0-1.
* Expected survival of ≥ 6 months
* Adequate organ reserve function.
Exclusion Criteria:
* Malignant disease other than gastric cancer (excluding radically treated basal cell carcinoma of the skin, squamous epithelial carcinoma of the skin, and/or radically resected carcinoma in situ) diagnosed within 5 years.
* Known Her-2 positive( IHC 3+ or FISH positve).
* Patients have received immunotherapy, such as PD-1 antibody, PD-L1 antibody and CTLA4 antibody
* Severe allergic reaction to monoclonal antibody.
* Receiving systemic glucocorticoid therapy within 7 days prior to the first dose of the study
* Known endoscopic signs of active bleeding from the lesion
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT06250894
Study Brief:
Protocol Section:
NCT06250894