Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:45 AM
Ignite Modification Date:
2025-12-25 @ 1:45 AM
NCT ID:
NCT03971994
Eligibility Criteria:
Inclusion Criteria:
* Healthy volunteers :
* Affiliation to social security
* Medical examination before study participation
* No contraindication to MRI
* Informed consent signed
* Young adults older than 18 years and younger than 40 years
* Healthy old adults older than 65 years and younger than 95 years
* Visual acuity allowing normal perception of stimuli or corrected to normal vision
* Patients with Alzheimer's Disease :
* Affiliation to social security
* Medical examination before study participation
* No contraindication to MRI
* Informed consent signed
* Patients with Alzheimer's Disease at mild or moderate stage (National Institute on Aging and Alzheimer's Association criteria), diagnosed at Grenoble CMRR (Centre Mémoire de Ressources et de Recherche)
* Patients older than 65 years and younger than 95 years
* MMSE (Mini-Mental State Examination) \> 18/30
* Ability to understand study instructions and give an informed consent
* Visual acuity allowing normal perception of stimuli or corrected to normal vision
Exclusion Criteria:
* Every participant having a vascular stent implanted less than 6 weeks before study
* Every participant having a biomedical material implanted that is considered "unsafe" in the list: http://www.mrisafety.com/TheList\_search.asp
* Every acquisition procedure not respecting required conditions by the "conditional" usage in a participant having a biomedical material implanted that is considered "conditional" in the list: http://www.mrisafety.com/TheList\_search.asp
* Every subject having a biomedical material such as a cardiac, neuronal or sensorial stimulator (cochlear implant because of demagnetization, electrode heating or artefact risk) or a ventricular drain without trained medical or paramedical support during MRI for these participants
* Ferromagnetic object inside the eye or the skull, close to nervous structures (displacement and complications risk such as eye or brain damage)
* Claustrophobia
* Psychiatric (e.g., bipolar disorder) or neurological pathology (e.g., epilepsy, Parkinson's Disease) other than Alzheimer's Disease
* Non cooperating participant
* Severe and uncontrolled affection: cardiac, respiratory, haematological, renal, hepatic, cancerous
* Participation to other research protocols with exclusion period or MRI during the past weel
* Drug therapy likely to modulate brain activity : neuroleptics, lithium, etc...
* Alcohol ingestion before study
* Participants concerned by articles L1125-5 to L1121-8 of CSP (Code de la Santé Publique) (pregnant or nursing women, underage or protected adult, person under administrative or judicial oversight
* Participant receiving more than 4500 euros for his participation to other studies involving human person during the past 12 months before this study
* Participant unable to be contacted in case of emergency
* Inability to understand study instructions or give an informed consent
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
95 Years
Study:
NCT03971994
Study Brief:
Protocol Section:
NCT03971994