Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:45 AM
Ignite Modification Date:
2025-12-25 @ 1:45 AM
NCT ID:
NCT04553094
Eligibility Criteria:
Inclusion Criteria:
* patient with Marfan syndrome and followed up at Bichat Claude Bernard hospital, Paris. Marfan syndrome should be diagnosed according to the Ghent nosology revised in 2010
* Patient taking protective treatment for the aorta (beta blocker, calcium channel blocker, ACE inhibitor, angiotensin II receptor antagonist).
* Valid patient, able to return to consultation and carry out functional assessments and personalized physical training at home.
* Patients operated prophylactically on the ascending aorta may be included at a distance \> 6 months from their surgery.
Exclusion Criteria:
* Myocardial pathology other than Marfan syndrome.
* Thoracic aorta dissection.
* Aortic diameter \> 45 millimeters.
* Uncontrolled high blood pressure at rest (systolic blood pressure \> 140 Millimeter of mercury and diastolic blood pressure \> 90 Millimeter of mercury)
* Increase in systolic blood pressure \> 160 Millimeter of mercury during exercise.
* Pregnancy at the time of the study
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT04553094
Study Brief:
Protocol Section:
NCT04553094