Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:43 AM
Ignite Modification Date:
2025-12-25 @ 1:43 AM
NCT ID:
NCT00497094
Eligibility Criteria:
Inclusion Criteria:
* Atherosclerosis is the underlying disease
* Patients with an asymptomatic stenosis \>80% (NASCET) with a documented progression of the degree of stenosis to \>80% within 6 months with a very tight stenosis ≥90% at initial presentation with a \>80% stenosis plus silent ipsilateral ischemia documented by CCT or MRI with ipsilateral \>80% stenosis plus contralateral \>80% stenosis or occlusion with \>80% stenosis plus planned major surgery
* Neurologist´s explicit consent to potentially perform CAS
Exclusion Criteria:
* Inability to provide informed consent
* Underlying disease other than atherosclerosis (inflammatory or autoimmune disease)
* Traumatic or spontaneous carotid dissections
* Life expectancy \<6 months
* Advanced dementia
* Advanced renal failure (serum creatinine \>2.5 mg/dL)
* Unstable severe cardiovascular comorbidities (e.g. unstable angina, heart failure)
* Restenosis after prior CAS or CEA
* Allergy or contraindications to study medications (clopidogrel, statins, ASA)
Healthy Volunteers:
False
Sex:
ALL
Study:
NCT00497094
Study Brief:
Protocol Section:
NCT00497094