Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:43 AM
Ignite Modification Date:
2025-12-25 @ 1:43 AM
NCT ID:
NCT05654194
Eligibility Criteria:
Inclusion Criteria:
* Newly diagnosed AML according to the WHO (2016) classification of acute myeloid leukemia.
* Age ≥ 18years.
* ECOG score: 0-3.
* White blood cell count ≤ 25\*10\^9/L
* Total bilirubin ≤ 3X the institutional upper limit of normal if attributable to hepatic infiltration by neoplastic disease
* AST (SGOT) and ALT (SGPT) ≤ 3X the institutional upper limit of normal
* Creatinine clearance ≥30ml/min
Exclusion Criteria:
* Pregnancy or lactation.
* Acute promylocytic leukemia or chronic myeloid leukemia in blast crisis.
* Another malignant disease.
* Uncontrolled active infection.
* Left ventricular ejection fraction \< 0.3 by echocardiography or grade III/IV cardiovascular dysfunction according to the New York Heart Association Classification.
* Active hepatitis B or hepatitis C infection.
* HIV infection.
* Other commodities that the investigators considered not suitable for the enrollment.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05654194
Study Brief:
Protocol Section:
NCT05654194