Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:43 AM
Ignite Modification Date:
2025-12-25 @ 1:43 AM
NCT ID:
NCT00134394
Eligibility Criteria:
Inclusion Criteria
* Adults 18 years or older with moderate to severe psoriasis, who are candidates for systemic or phototherapy, with a baseline score of 6 or higher on the target lesion score, and a baseline score of 3 or higher on the Physician's Global Assessment, on each side of the body
* Patients who are already on a stable dose of etanercept for at least 2 months and have the above criteria
* Subjects must have target lesions on each side of the body that are at least 1.5 cm in diameter and roughly symmetrical in appearance and location
Exclusion Criteria
* Inability to understand consent or comply with study requirements
* Pregnancy or unwillingness to use adequate birth control method
* Lactation
* Psoriasis plus ultraviolet A (PUVA) or systemic therapy within the past 4 weeks (other than a stable dose of Enbrel for at least 2 months)
* Ultraviolet B (UVB) or topical therapy (other than over-the-counter moisturizers) within the past 2 weeks
* Active tuberculosis or other opportunistic infection
* Demyelinating disease
* Uncontrolled congestive heart failure
* Known allergy to or any contraindications to using topical tacrolimus or etanercept
* Lack of insurance coverage or inability/refusal to pay out of pocket for etanercept and standard of care laboratory tests and PPD/CXR
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00134394
Study Brief:
Protocol Section:
NCT00134394