Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:41 AM
Ignite Modification Date:
2025-12-25 @ 1:41 AM
NCT ID:
NCT04946994
Eligibility Criteria:
Inclusion Criteria:
* confirmed HIV infection
* sedentary lifestyle, defined as self-reported physical activity that breaks a sweat \<3 days/week, with no regular resistance exercise for 3 months prior to the study
* on a current, modern antiretroviral therapy (ART) (anti-retroviral regimen)
* documented HIV-1 RNA \<200 copies/mL in the past 12 months
* willing to engage in a supervised exercise program 3 times/week for 16 weeks
* poor sleep quality based on self-report survey (Pittsburgh Sleep Quality Index, total score \>5)
* aged ≥ 50 years
* English speaking
Exclusion Criteria:
* not controlled hypertension-defined as resting systolic blood pressure \>150 mmHg or diastolic blood pressure \>90 mmHg; participants who do not meet these criteria at first screening will be re-evaluated, including follow-up evaluation by their primary care provider with initiation or adjustment of anti-hypertensive medications
* Indicators of unstable ischemic heart disease (e.g., angina, ST segment depression) or serious arrhythmias-at rest or during the graded exercise test without negative follow-up evaluation will be cause for exclusion; follow-up evaluation must include diagnostic testing (e.g., thallium stress test) with interpretation by a cardiologist
* New York Heart Association Class III or IV congestive heart failure, clinically significant aortic stenosis, uncontrolled angina, or uncontrolled arrhythmia
* Pulmonary disease-requiring the use of supplemental oxygen at rest or with physical exertion
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Study:
NCT04946994
Study Brief:
Protocol Section:
NCT04946994