Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:40 AM
Ignite Modification Date:
2025-12-25 @ 1:40 AM
NCT ID:
NCT06584994
Eligibility Criteria:
Inclusion criteria:
* Minimum of child affected with cancer pre-disposition syndromes and their father
* Additional family members of consented father and child duos (Mother, same parent siblings, Maternal/Paternal Aunts, uncles and grandparents of affected child)
* Reproductive tissue samples from both men and women affected by cancer collected with consent for use in research.
* Reproductive tissue samples from both men and women unaffected by cancer collected with consent for use in research.
Exclusion:
* Fathers who do not wish to donate a semen sample or are unable to will be excluded from the study, as will their families
* Fathers who have had a vasectomy will be excluded from the study as will their families
* Adults who do not have the capacity to consent for themselves will be excluded from the study.
* Families in which both parents do not have capacity to consent will also be excluded as they will be unable to give parental consent for their children's participation.
* In order to be eligible siblings must share the same two parents as the affected child, all other siblings will be excluded from the study.
* Male relatives in the extended family (Maternal/Paternal Aunts, uncles and grandparents of affected child) unwilling or unable to donate both a blood or saliva sample and a semen sample will be excluded from the study.
* Participants who do not have a good understanding of the English language will be excluded from the study.
Healthy Volunteers:
True
Sex:
ALL
Study:
NCT06584994
Study Brief:
Protocol Section:
NCT06584994