Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:40 AM
Ignite Modification Date:
2025-12-25 @ 1:40 AM
NCT ID:
NCT02153294
Eligibility Criteria:
Inclusion Criteria:
* Admission to an ICU participating in this trial
* Need for intubation
* Within 1 hour of admission from the operation room or emergency room (if still intubated and ventilated), or within 1 hour of start of invasive ventilation in the ICU
* An expected duration of ventilation \> 24 hours
Exclusion Criteria:
* Age less than 18 years
* Patients previously randomized in PReVENT
* Patients participating in other interventional trials
* Patients with a clinical diagnosis of ARDS according to the Berlin definition
* Patients with a PaO2/FiO2 \< 200 mm Hg in whom hypoxia is presumably not caused by cardiac failure or fluid overload
* Invasive ventilation longer than 12 hours directly preceding admission
* Patients with suspected or confirmed pregnancy
* Patients with increased and uncontrollable intracranial pressure (of ≥18 mmHg)
* Patients with GOLD classification III or IV chronic obstructive pulmonary disease (COPD)
* Patients with asthmatic status
* Patients with premorbid restrictive pulmonary disease (evidence of chronic interstitial infiltration on previous chest radiographs)
* Patients with new proven pulmonary thrombo-embolism
* Patients with any previous pneumectomy or lobectomy
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
100 Years
Study:
NCT02153294
Study Brief:
Protocol Section:
NCT02153294