Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:39 AM
Ignite Modification Date:
2025-12-25 @ 1:39 AM
NCT ID:
NCT02765594
Eligibility Criteria:
Inclusion Criteria:
1. biopsy proven primary IgA nephropathy
2. age 18-60 years
3. proteinuria range from 0.5 to 1.5g/d
4. serum creatinine ≤132.6μmol/L
5. normal blood pressure or blood pressure ≤130/80 mmHg in patients with hypertension
Exclusion Criteria:
1. Hypersensitivity to chloroquine or to hydroxychloroquine
2. blood pressure \<90/60 mm Hg
3. pregnancy and breastfeeding women
4. renal artery stenosis
5. Rapidly progressive renal insufficiency
6. systemic lupus erythematosus or other connective tissue diseases
7. Henoch- schoenlein purpura
8. other nephritis
9. diabetes mellitus
10. retinopathy
11. other contraindication of hydroxychloroquine
12. severe hepatic insufficiency
13. G6PD deficiency
14. psoriasis or porphyria
15. malignant hypertension
16. viral hepatitis or other infections
17. treatment with steroids or cytotoxic drugs during the previous three months
18. psychiatric disorder
19. not suitable for the study judged by investigator
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT02765594
Study Brief:
Protocol Section:
NCT02765594