Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:39 AM
Ignite Modification Date:
2025-12-25 @ 1:39 AM
NCT ID:
NCT05980494
Eligibility Criteria:
Inclusion Criteria:
* Patients on mechanical ventilation (MV).
* Aged more than 18 years.
* Mean arterial pressure (MAP) less than 65 mmHg or systolic arterial pressure less than 90mm Hg with signs of hypoperfusion (urinary flow \< 0.5mL/kg/ h for \> 2hr , tachycardia \> 100 beats/min, or presence of skin mottling , and seurm lactate more than 2 mmol/L).
Exclusion Criteria:
* Cardiac arrhythmias.
* Previously known significant valvular disease or intracardiac shunt.
* Chest drains.
* Increasing intra abdominal pressure.
* Prephiral vascular disesaes.
* Adult respiratory distress syndrome (ARDS) patients due to low tidal volume.
* Interstitial lung disease because B-lines in these conditions are the consequence of the thickened interlobular septa characterizing fibrosis and are not modified by the state of hydration or imbibition 12
* Any contraindication for fluid administration as cardiogenic shock, acute pulmonary edema or LVEF% less than 50%.
* Renal patients with oliguria and volume overload including patients on hemodialysis or patients with acute anuric renal failure.
* Patients with lower extremity artery/vein thrombosis, significant lower extremity artery plaque, lower extremity artery occlusion, inferior vena cava filter implantation and lower extremity varicose veins.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05980494
Study Brief:
Protocol Section:
NCT05980494